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    by: sanjai_dash

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    1 : Clinical Profile Of Dengue During 2011 Outbreak in Angul
    2 : Clinical Profile Of Dengue During 2011 Outbreak in Angul DR SANJAY DASH MD (Med) CHIEF MEDICAL OFFICER NEHRU SHATABDI CENTRAL HOSPITAL MAHANADI COALFIELDS LIMITED
    3 : OVERVIEW OF THEMES Introduction Aims and Objectives Materials and Methods Results Conclusions
    4 : Introduction Dengue fever (DF)-Commonest viral infection spread by Aedes mosquitoes. Causes significant morbidity & mortality. Present in over 100 tropical and sub-tropical countries covering 2.5 billion people. Estimated Annual Global Stats-50 m cases,0.5 m hospitalizations & 2.5% deaths. Two Severe forms—Dengue haemorrhagic fever (DHF) and Dengue shock syndrome (DSS).
    5 : DENGUE Dengue / DHF is widely prevalent in India and all the 4 serotypes are found Data on the natural history and outcome of Dengue in adults is quite limited in Odisha. Dengue was unheard of in the district of Angul, the industrial hub of Odisha. An outbreak of Dengue fever occurred in the month of Late July 2011 which continued till late September 2011.
    6 : DENGUE Aims and objectives: To study clinical and laboratory findings in adult Dengue Patients hospitalized at Talcher Odisha. Design: It is a prospective observational study.
    7 : DENGUE Clinical, laboratory and demographic information were collected from Adult Patients with confirmed dengue infections (n116) treated at Nehru Shatabdi Central Hospital, Talcher. Cases reported from Aug to Sept 2011 were included in the study .
    8 : Diagnosis Dengue fever WHO Criteria Probable diagnosis: Acute febrile illness with two or more of the following : 1 Headache 2 Retro-orbital pain 3 Myalgia 4 Arthralgia/bone pain 5 Rash 6 Haemorrhagic manifestations 7 Leucopenia (TLC =5000cells/mm3) 8 Thrombocytopenia (TPC <150 000 cells/mm3) 9 Rising PCV (5-10%). And at least one of following: Supportive serology on single serum sample: titre =1280 with HI test, comparable IgG titre with Elisa, or testing positive in IgM antibody test, and Occurrence at the same location and time as confirmed cases of DF.
    9 : Diagnosis Confirmed diagnosis: Probable case with at least one of the following: Isolation of dengue virus from serum, CSF or autopsy samples. Fourfold or greater increase in serum IgG or increase in IgM antibody specific to dengue virus. Detection of dengue virus or antigen in tissue, serum or CSF . We diagnosed either by IgM Elisa or NS1 Elisa.
    10 : Demographic Profile
    11 : Manifestations
    12 : Important Parameters
    13 : Outcome
    14 : Conclusions Dengue is one of the most important Mosquito borne viral infections. In the present study also commonest manifestations were fever, headache and flushing. Urticaria and Serous Effusions were seen in only a minority.
    15 : Conclusions 113 out of 116 Patients recovered. 3 Patients succumbed. Most of the case were DF with very few DHF and DSS. This being the first known outbreak of DF in Talcher, more adults suffered.
    16 : Conclusions Early recognition, careful monitoring and appropriate therapy – reduces mortality. As Newer areas are being affected regularly Health care providers must have thorough Knowledge regarding the various presentations of dengue infection.
    17 :

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